细胞外信号放大器
DAM50细胞外信号放大器
仪器简介
WPI公司DAM50细胞外信号放大器是最早用于细胞外信号记录的设备，每一个设备都配备可选的高通和低通滤波器，并由9伏特电池操作，既可以AC也可以DC耦合记录的优势是输出绝对的电压水平，最常用于细胞内信号和传感器信号灯的记录。而AC耦合的记录由于DC基线被高通滤波消除，因此主要用于神经元细胞快速变化的动作电位信号记录，同时也可以用于ECG、EEG、EMG和EOG的记录。DAM50细胞外信号放大器可以作为独立的单元，放置于任何桌面江西操作，也可以通过可选的固定仪器配件将其固定在某个仪器区域使用。
仪器应用
■用于小动物包括大鼠、小鼠和豚鼠等脑电图信号记录；
■用于小动物包括大鼠、小鼠和豚鼠等心电图信号记录；
■用于动物在体和离体神经、肌肉等动作电位的记录
■用于小动物包括果蝇等视网膜电图的记录；
■用于小动物包括大鼠、小鼠和豚鼠等在体和离体肌肉电生理信号的记录；
■用于小动物包括大鼠、小鼠和豚鼠等肠电图信号记录；
DAM80细胞外信号放大器
仪器简介
DAM80是唯一一个交流放大器，具有的特征包括一个远程、低噪音的前级放大器，它可以安装在微操上用于近距离、在体皮层记录、组织切片或其他使用高阻抗玻璃或金属微电极的应用场合。
其他特征包括：
外部指定控制或在面板上江西手术操作产生电流用于组织标记，或有限的离子电泳和细胞刺激；
内置电池测试功能；
使用WPI公司3485、3484等可选固定配件可以非常方便地将放大器放置于固定的工作区域内。
仪器应用
■用于小动物包括大鼠、小鼠和豚鼠等肌电图信号记录；
■用于小动物包括大鼠、小鼠和豚鼠等心电图信号记录；
■用于动物在体和离体神经、肌肉等动作电位的记录
■用于小动物包括果蝇等视网膜电图的记录；
■用于小动物包括大鼠、小鼠和豚鼠等肠电图信号记录；
■用于小动物包括大鼠、小鼠和豚鼠等脑电图信号记录；
ISO-80细胞外信号放大器
仪器简介
ISO-80细胞外信号放大器是一款高效、隔离的差分细胞外信号放大器，设计用于在体和离体的神经、肌肉细胞动作电位的记录，其他功能包括测量电极阻抗、组织标记、组织刺激和电极的清洗应用。
该设备是一款有电池供电、低噪音、交流耦合的从电器上与主电源和接地线隔离的差分放大器，ISO-80配有一个远程有源探头（1米长电线），该探头整合有电极阻抗测试功能和一个常电流刺激器，常用电流刺激器可以用于细胞标记、刺激或电极清洗。ISO-80最典型的应用包括测量脑电图、心电图、细胞外信号和动作电位，ISO-80为了改进噪音抑制进行了电磁屏蔽，它也使用了高通和低通滤波器，增益从100倍到10000倍，最低的低通设置是5Hz，最高的高频设置为10000 Hz。
仪器应用
■用于小动物包括大鼠、小鼠和豚鼠等肌电图信号记录；
■用于小动物包括大鼠、小鼠和豚鼠等心电图信号记录；
■用于动物在体和离体神经、肌肉等动作电位的记录
■用于小动物包括果蝇等视网膜电图的记录；
DAM50参考文献
[1] A calpain-2 selective inhibitor enhances learning & memory by prolonging ERK activation[J]. Y Liu et al., Neuropharmacology, 2016, 105:471-477.
[2] Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson’s Disease[J]. S Ztaou et al., Journal of Neuroscience, 2016, 36(35).
[3] TRPV1 Channels and Gastric Vagal Afferent Signalling in Lean and High Fat Diet Induced Obese Mice[J]. SJ Kentish et al., Plos One, 2015, 10(8):e0135892.
[4] How We Teach: Classroom And Laboratory Research Projects Investigation of blood flow and the effect of vasoactive substances in cutaneous blood vessels of Xenopus laevis[J].
Škorjanc A et al., Advances in Physiology Education, 2015, 39(2):91-5.
[5] Supplemental Information Optogenetic and Electrical Microstimulation Systematically Bias Visuospatial Choice in Primates[J]. Ji Dai et al., Current Biology Cb, 2014, 24( 1) :63-9.
[6] Distinct spatiotemporal activity in principal neurons of the mouse olfactory bulb in anesthetized and awake states[J]. DG Blauvelt et al., Frontiers in Neural Circuits, 2013, 7( 1):46.
[7] Long-term potentiation of perforant pathway-dentate gyrus synapse in freely behaving mice[J]. Blaise, J. H. Journal of Visualized Experiments, 2013(81):e50642-e50642.
[8] Fatal neurological respiratory insufficiency is common among viral encephalitides[J].
H Wang et al., The Journal of Infectious Diseases, 2013, 208(4) :573-583.
[9] In Vivo Confocal Intrinsic Optical Signal Identification of Localized Retinal Dysfunction[J].
QX Zhang et al., Investigative Opthalmology & Visual Science, 2012, 53( 13), 8139.
[10] Mutants in Drosophila TRPC channels reduce olfactory sensitivity to carbon dioxide[J].
F Badsha et al., PloS One, 2012, 7( 11), e49848.
[11] Muscle power attenuation by tendon during energy dissipation[J].
N Konow et al., Proceedings of the Royal Society B Biological Sciences, 2012, 279(279): 1108- 13.
[12] Optogenetic analysis of neuronal excitability during global ischemia reveals selective deficits in sensory processing following reperfusion in mouse cortex[J].
[13] Neurological suppression of diaphragm electromyographs in hamsters infected with West Nile virus[J]. H Wang et al., Journal of NeuroVirology, 2010, 16(4):318-329.
[14] Neuroplasticity ofthe central hypercapnic ventilatory response: teratogen-induced impairment and subsequent recovery during development[J]. CM Brundage et al., Developmental Neurobiology, 2010, 70( 10):726–735.
[15] Growth hormone rescues hippocampal synaptic function after sleep deprivation[J].
E Kim et al ., American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 2010, 298(6), R1588-96.
[16] Hearing in Drosophila requires TilB, a conserved protein associated with ciliary motility[J]. RG Kavlie et al., Genetics,2010, 185( 1), 177–88.
[17]N-Methyl-D-Aspartate Induces Cortical Hyperemia through Cortical Spreading Depression-Dependent and -Independent Mechanisms in Rats[J]. L Lenti et al., Microcirculation, 2009, 16(7), 629–639.
[18] Sympathetic-correlated c-Fos expression in the neonatal rat spinal cord in vitro[J].
CK Su et al., Journal of Biomedical Science, 2009, 16( 1), 44.
[19] Timing and duration of developmental nicotine exposure contribute to attenuation of the tadpole hypercapnic neuroventilatory response[J]. CM Brundage et al., Developmental Neurobiology, 2009, 69(7), 451–461.
[20] An essential role for endocytosis of rhodopsin through interaction of visual arrestin with the AP-2 adaptor[J].
NR Orem et al., Journal of Cell Science, 2006, 119(Pt 15):3141.
[21] Adrenocorticotropic hormone enhances the masculinity of an electric communication signal by modulating the waveform and timing of action potentials within individual cells[J].
[22] Cerebellar norepinephrine modulates learning of delay classical eyeblink conditioning: Evidence for post-synaptic signaling via PKA[J]. MC Cartford et al., Learning & memory (Cold Spring Harbor, N.Y.), 2004, 11(6):732.
DAM80参考文献
[1] Serotonin in the solitary tract nucleus shortens the laryngeal chemoreflex in anaesthetized neonatal rats[J]. Donnelly W T et al., Experimental Physiology, 2016, 101(7), 946–961.
[2] Optogenetic activation of mechanically insensitive afferents in mouse colorectum reveals chemosensitivity[J]. Feng B et al., American Journal of Physiology - Gastrointestinal and Liver Physiology, 2016, 310( 10).
[3] Responses of infrared-sensitive tectal units of the pit viper Crotalus atrox to moving objects[J]. Kaldenbach F et al., Journal of Comparative Physiology A, 2016, 202(6), 389–398.
[4] Acid Sensitive Ion Channels as Target of Hydrogen Sulfide in Rat Trigeminal Neurons[J].
Mustafina A N et al., BioNanoScience, 2016, 1–3.
[5] Commissural Gain Control Enhances the Midbrain Representation of Sound Location[J].
[6] The Binaural Interaction Component in Barn Owl (Tyto alba) Presents few Differences to Mammalian Data[J]. Palanca-Castan N et al., Journal of the Association for Research in Otolaryngology, 2016, 1– 13.
[7] Functional Characterization of Mouse Colorectal Afferent Endings[J].
Feng B et al., Journal of Visualized Experiments, 2016, (95), e52310–e52310.
[8]Chronic sodium salicylate administration enhances population spike long-term potentiation following a combination of theta frequency primed-burst stimulation and the transient application of pentylenetetrazol in rat CA1 hippocampal neurons[J].
Gholami M et al., European Journal of Pharmacology, 2015, 767, 165– 174.
[9] The role of TRPC6 in seizure susceptibility and seizure-related neuronal damage in the rat dentate gyrus[J]. Kim Y J et al., Neuroscience, 2015, 307, 215–230.
[10] Taurine supplementation prevents the adverse effect ofhigh sugar intake on arterial pressure control after cardiac ischemia/reperfusion in female rats[J]. Kulthinee S et al., Advances in Experimental Medicine and Biology, 2015, 803, 597–611.
[11] Manganese-Induced Atypical Parkinsonism Is Associated with Altered Basal Ganglia Activity and Changes in Tissue Levels of Monoamines in the Rat[J]. Bouabid S et al., PLoS ONE, 2014, 9(6), e98952.
[12] Sensory Arsenal on the Stinger of the Parasitoid Jewel Wasp and Its Possible Role in Identifying Cockroach Brains[J].
Gal R et al., PLoS ONE, 2014, 9(2), e89683.
[13] Neurovascular coupling and decoupling in the cortex during voluntary locomotion[J].
[14] Ememory failure induced by systemic immune challenges[J]. Hermann P M et al., BMC Neuroscience, 2013, 14( 1), 83. Kam T I et al., The Journal of Clinical Investigation, 2013, 123(7), 2791–802.
[16] Activation of the central nervous system induced by micro-magnetic stimulation[J].
Park H J et al., Nature Communications, 2013, 4, 2463.
[17] Complementary processing ofhaptic information by slowly and rapidly adapting neurons in the trigeminothalamic pathway. Electrophysiology, mathematical modeling and simulations of vibrissae-related neurons[J]. Sanchez-Jimenez A et al., Frontiers in Cellular Neuroscience, 2013, 7, 79.
[18]E Sotoyama H et al., Journal of Neurochemistry, 2013, 126(4), 518–28.
[19] Impaired renal response to portal infusion of hypertonic saline in adriamycin-treated rats[J].
Jirakulsomchok D et al., Clinical and Experimental Pharmacology and Physiology, 2016, 39(7), 636–641.
[20]Photosensitive-polyimide based method for fabricating various neural electrode architectures[J]. Kato Y X et al., Frontiers in Neuroengineering, 2012, 5.
[21] Effects of milnacipran, a 5-HT and noradrenaline reuptake inhibitor, on C-fibre-evoked field potentials in spinal long-term potentiation and neuropathic pain[J]. Ohnami S et al., British Journal of Pharmacology, 2012, 167(3), 537–47.Razy-Krajka F et al., BMC Biology, 2012, 10( 1), 45.
[23] High-frequency electrical stimulation in the nucleus accumbens ofmorphine-treated rats suppresses neuronal firing in reward-related brain regions[J].
